March 12, 200817 yr I DONT WANT A LARGE FARVA http://i49.photobucket.com/albums/f258/Turk3102/farva.jpg
March 13, 200817 yr sp0rk;551126']Coke and dxm are fine and I should know since I've done it and I've done dxm with amphetamines and dextroamphetamine. Same with rolls and dxm I've been there and done that. I wouldn't do coke, speed, meth, or rolls without dxm anymore because all those drugs have been proven to be toxic in some way and dxm just happens to be very good at preventing negative side effects from a number of drugs. DXM has been shown to prevent the excitotoxicity caused by those drugs, prevent serotonin/dopamine depletion that would normally occur, reduce addiction potential of stims and nicotine, and does a nice job of potentiating a lot of drugs. Honestly you should educate yourself a bit on this stuff (look on PUBMED for a start) instead of simply having the usual druggie knee jerk reaction of OMG NO DONT DO THIS + THIS. Spelling serotonin wrong, among other things, isn't doing you any favors. I'm not trying to be super mean or anything nor am I saying that you should go do 900mg of DXM, smoke meth, then snort a g of powder or anything like that. I'm saying that if you know yourself and your source then you can be a smart and functional drug user and it's not hard at all to look around and figure things out yourself. Honestly I think too many people nowadays just want to 'get fucked up' and don't care but I'd rather be smart about shit. Well I wasn't sure about the coke and dxm just sounded bad. On the spelling thing? That's just petty, holy shit I spelt serotonin wrong omg. Seriously though, not just the normal stoner "BAD COMBO LOLOL" just because you've done them and you didn't die dosen't mean they aren't safe. If you are gonna mix e and dxm be my guest, but there are a number of sources that will confirm what I said: "Furthermore, DXM is contraindicated with MDMA. It is a both a serotonin releaser and a reuptake inhibitor, as well as being metabolized by the same liver enzyme as MDMA, thus preventing the proper breakdown of MDMA. Furthermore, DXM inhibits perspiration, elevating body temperature. Combining DXM and MDMA, therefore, significantly increases ones chance of "serotonin syndrome," a rare but potentially fatal condition. " -http://www.maps.org/news-letters/v09n4/09447sfe.html "Both also stimulate the release of serotonin and can produce serotonin syndrome (a potentially fatal condition that is easily confused with heatstroke)." -http://drugs.greenparty.org.uk/substance/dxm.php To the best of my knowledge it is a bad combo. The coke and opiate was going out on a limb though, my apologies for putting in something that I didn't have solid evidence to back up. Also I spelled serotonin wrong because I rely on firefox spellcheck lol.
March 13, 200817 yr Author Since you insist mdma and dxm is bad I'll just post this one report and let you find the many others supporting it and referencing it. Though the report below uses dextrorphan, a dxm metabolite, what it says of course applies to dxm as well. http://www.ncbi.nlm.nih.gov/pubmed/2574428 "The N-methyl-D-aspartate (NMDA) receptor antagonist, dextrorphan, prevents the neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA) in rats. Finnegan KT, Skratt JJ, Irwin I, Langston JW. Institute For Medical Research, San Jose, CA 95128. Using the systemically active, non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist dextrorphan, we explored the role of the NMDA receptor-calcium channel complex in the toxic mechanism of action of 3,4-methylenedioxymethamphetamine (MDMA). Rats were treated with MDMA, dextrorphan, or the combination of MDMA and increasing doses of dextrorphan, and then killed 10 days later for the assay of serotonin and dopamine in the striatum, hippocampus, and cortex. Dextrorphan totally prevented the serotonin-depleting effects of MDMA in the straitum, with a lessened but still significant blockade noted in the hippocampus and cortex. These findings may provide a clue to the molecular events underlying MDMA-induced neurotoxicity. PMID: 2574428 [PubMed - indexed for MEDLINE]" You quoted from the DanceSafe report on maps.org regarding why dxm and mdma make for a bad combo and in fairness it's definitely risky in the context of a hot rave, multiple pills, unknown dosages, and general lack of knowledge of the effects and how to best handle them. But as I said already if you know yourself and your source and learn as much as you can before just ingesting drugs at random then you can be a much better drug user. I'll give you this and say that yea you really don't want people mixing dxm and e like that but that wasn't how I meant for it to be done anyways. I personally chose to take dxm with my rolls and I knew how much I was taking, how to handle it, and was prepared to do it and I frankly have found it to be quite beneficial.
March 13, 200817 yr takeshiSC needs to stop stealing my thunder, you chink asshole. PS: will you make me an anime sig that looks alot like sp0rks.
March 13, 200817 yr http://img509.imageshack.us/img509/255/120537649597zd6.gif Grip n sip sum lean rather!
March 13, 200817 yr Author http://img509.imageshack.us/img509/255/120537649597zd6.gif Grip n sip sum lean rather! That pic makes me wish I had a bag of jolly ranchers now. :(
March 13, 200817 yr Banfelt;551314']takeshiSC needs to stop stealing my thunder, you chink asshole. PS: will you make me an anime sig that looks alot like sp0rks. Sometimes I even remember to sign onto IRC. If you want a sig that looks like sp0rks, I want you to get on your knees and beg for forgiveness.
March 13, 200817 yr Id be happy to, but when i type "like sp0rkys" i mean same as his except cross out sp0rky and write banfelt.
